Lambda Light Chain Antibody (HP6054), Alexa Fluor™ 532, Novus Biologicals™

Lambda Light Chain

Monoclonal

Alexa Fluor 532

50 mM sodium borate with 0.05% sodium azide

IGLC1

Purified human IgG myeloma proteins coupled to polyaminostyren microbeads.

0.1 mL

Primary

This monoclonal antibody is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Store at 4°C in the dark.

Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

HP6054

Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

IGLC, immunoglobulin lambda constant group

Mouse

Protein A or G purified

Adaptive Immunity, Immunology

3537.0

Human

IgG2a κ