VEGFR1/Flt-1 Antibody (FLT1/658), Alexa Fluor™ 350, Novus Biologicals™

VEGFR1/Flt-1

Monoclonal

Alexa Fluor 350

50 mM sodium borate with 0.05% sodium azide

FLT1

Recombinant human VEGFR1/Flt-1 protein (Uniprot: P17948)

0.1 mL

2321

Human

IgG1 κ

ELISA

FLT1/658

ELISA

EC 2.7.10, EC 2.7.10.1, FLT, FLT-1, Fms-like tyrosine kinase 1, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor), FRT, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, vascular endothelial growth factor receptor 1, Vascular permeability factor receptor, VEGFR1, VEGFR-1

Mouse

Protein A or G purified

Primary

Three cell membrane receptor tyrosine kinases, Flt-1 (also designated VEGF-R1), Flk-1 (also designated VEGF-R2) and Flt-4, putatively involved in the growth of endothelial cells, are characterized by the presence of seven immunoglobulin-like sequences in their extracellular domain. These receptors exhibit high degrees of sequence relatedness to each other as well as lesser degrees of relatedness to the class III receptors including CSF-1/Fms, PDGR, SLFR/Kit and Flt-3/Flk-2. Two members of this receptor class, Flt-1 and Flk-1, have been shown to represent high affinity receptors for vascular endothelial growth factors (VEGFs). On the basis of structural similarity to Flt-1 and Flk-1, it has been speculated that Flt-4 might represent a third receptor for either VEGF or a VEGF-related ligand.

Store at 4°C in the dark.