CD31/PECAM-1 Antibody (C31.12), Alexa Fluor™ 594, Novus Biologicals™

CD31/PECAM-1

Monoclonal

Alexa Fluor 594

50 mM sodium borate with 0.05% sodium azide

PECAM1

Recombinant human CD31/PECAM-1 protein (Uniprot: P16284)

0.1 mL

5175

Human

IgG1 κ

Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence

C31.12

Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence

adhesion molecule, CD31, CD31 antigen, CD31/EndoCAM, EndoCAM, FLJ34100, FLJ58394, GPIIA′, PECA1, PECAM-1, PECAM-1, CD31/EndoCAM, platelet endothelial cell adhesion molecule, platelet endothelial cell adhesion molecule-1, platelet/endothelial cell adhesion molecule

Mouse

82.5 kDa

Primary

CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 monoclonal antibody reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.

Store at 4°C in the dark.