OP107100UG
MilliporeSigma™ anti-c-Myc Clone: 90000000000,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | OP107100UG-Each-of-1 | In Stock | ₹ 46,799.76 |
OP107100UG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,799.76
GST (18%): ₹ 8,423.957
Total Price: ₹ 55,223.717
Antigen
c-Myc
Classification
Monoclonal
Conjugate
Unconjugated
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Liquid
Applications
Flow Cytometry, Immunoblot, Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunoprecipitation
Clone
90000000000
Formulation
In 0.05M sodium phosphate buffer, 0.2% gelatin.
Immunogen
a synthetic peptide (AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA) corresponding to amino acids 408-439 of human c-Myc
Regulatory Status
RUO
Test Specificity
Recognizes the ∽60-67kDa c-Myc protein in HL60 cells and lung carcinoma tissue.
Content And Storage
2°C to 8°C
Isotype
IgG1
Related Products
Description
- Specifically detects c-Myc Clone: 90000000000 in Human, Mouse, Rat samples, and it is validated for Flow Cytometry, Immunofluorescence, Immunohistochemistry (Frozen), Immunoprecipitation, Immuno Blotting The v- myc oncogene, initially identified in the MC29 avian retrovirus, causes myelocytomas, carcinomas, sarcomas and lymphomas, and belongs to a family of oncogenes conserved throughout evolution
- In humans the family consists of five genes: c- myc , N- myc , R- myc , L- myc , and B- myc
- Amplification of the c- myc gene has been found in several types of human tumors including lung, breast and colon carcinomas, while the N- myc gene has been found amplified in neuroblastomas, small cell lung carcinomas and Wilms tumors
- L- myc is amplified in small cell lung cancer
- Immunological studies have shown that the human c- myc gene gives rise to at least two nuclear phosphoproteins of ∽64kDa and ∽67kDa that exhibit relatively short (30 min) half lives in vivo and exhibit DNA binding properties in vitro .