OP133100UG
MilliporeSigma™ anti-N-Myc Ab 1, Clone: NCM II 100,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | OP133100UG-Each-of-1 | In Stock | ₹ 61,151.90 |
OP133100UG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 61,151.90
GST (18%): ₹ 11,007.342
Total Price: ₹ 72,159.242
Antigen
N-Myc
Classification
Monoclonal
Conjugate
Unconjugated
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Form
Purified
Applications
Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunoprecipitation
Clone
NCM II 100
Formulation
In 50mM sodium phosphate buffer, 50% glycerol.
Immunogen
recombinant, human, N-myc fusion protein, expressed inE. coli
Regulatory Status
RUO
Test Specificity
Recognizes the N-myc protein and its cleavage product in IMR5 cells.
Content And Storage
−20°C
Isotype
IgG1
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Description
- Specifically detects N-Myc Clone: NCM II 100 in Human, Mouse samples, and it is validated for Immunofluorescence, Immunohistochemistry (Frozen), Immunoprecipitation, Immuno Blotting The v- myc oncogene, initially identified in the MC29 avian retrovirus, causes myelocytomas, carcinomas, sarcomas and lymphomas, and belongs to a family of oncogenes conserved throughout evolution
- In humans the family consists of five genes: c- myc , N- myc , R- myc , L- myc and B- myc
- Amplification of the N- myc gene has been found in human neuroblastomas and cell lines
- The extent of N- myc amplification correlates well with the stage of neuroblastoma disease
- Immunological studies have shown that the human N- myc gene gives rise to at least two nuclear phosphoproteins of ∽64kDa and ∽67kDa that exhibit relatively short (30 min) half lives in vivo and exhibit DNA binding properties in vitro .