Resistin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA11050-Each-of-1 | In Stock | ₹ 46,146.50 |
PA11050 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,146.50
GST (18%): ₹ 8,306.37
Total Price: ₹ 54,452.87
Antigen
Resistin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
RETN
Gene Alias
Adipose tissue specific secretory factor; adipose tissue-specific secretory factor; Adipose-specific cysteine-rich secreted protein A12-alpha; ADSF; C/EBP epsilon regulated myeloid specific secreted cysteine rich protein precursor 1; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 1; c/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein; cysteine-r; Cysteine-rich secreted protein A12-alpha-like 2; cysteine-rich secreted protein FIZZ3; dominant inhibitory adipocyte-specific secretory factor; dri; FIZZ3; found in inflammatory zone 3; HXCP1; MGC126603; MGC126609; Resistin; resistin delta2; RETN; RETN1; RSN; RSTN; UNQ407/PRO1199; XCP1; Xcp4
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
57264
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.
Q99P87
Gene Symbols
RETN
Immunogen
Synthetic peptide corresponding to residues S(21) S M P L C P I D E A I D K K I K Q D C(39) of mouse Resistin.
Quantity
200 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- PA1-1050 detects recombinant mouse resistin
- PA1-1050 has been successfully used in Western blot procedures
- By Western blot, this antibody detects an ∽14 kDa protein representing recombinant mouse resistin
- The PA1-1050 immunogen is a synthetic peptide corresponding to residues S(21) S M P L C P I D E A I D K K I K Q D C(39) of mouse Resistin
- This peptide (Cat
- # PEP-165) is available for use in neutralization and control experiments
- Adipose tissue is an energy reserve in animals and is strictly regulated
- Adipose cells produce and secrete numerous physiologically important proteins, such as lipoprotein lipase (LPL), leptin, adipocyte complement related protein of 30 kDa (Acrp30), perilipin, and resistin
- Resistin, also known as Adipocyte Secreted Factor (ADSF) and FIZZ3, is a cytokine that is specifically secreted by adipocytes
- While the function of resistin is not well understood, it appears to have key paracrine roles and has a suggested role in type 2 diabetes
- Studies show that in obese, diabetic mice the levels of serum resistin are increased, which has an antagonistic effect on insulin
- Additional studies have shown that resistin causes insulin resistance and glucose intolerance in mice
- Resistin gene expression requires C/EBP alpha, which is necessary and sufficient for expression
- Studies show that the coactivators CBP and p300, which have been shown to display histone acetyltransferase (HAT) activity, abundantly acetylate the histones at the resistin promoter suggesting their role in activating chromatin for resistin transcription
- Numerous PPAR gamma and RXR ligands have been shown to downregulate resistin expression in adipocytes.