SR-BI/SR-BII Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA132415-Each-of-1 | In Stock | ₹ 51,397.50 |
PA132415 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,397.50
GST (18%): ₹ 9,251.55
Total Price: ₹ 60,649.05
Antigen
SR-BI/SR-BII
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SCARB2
Gene Alias
85 kDa lysosomal membrane sialoglycoprotein; 85 kDa lysosomal sialoglycoprotein scavenger receptor class B, member 2; 9330185J12Rik; AI120173; AMRF; CD36; CD36 and LIMPII analogous 1; CD36 antigen (collagen type I receptor thrombospondin receptor)-like 1 (scavanger receptor class B type 1); CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II); CD36 antigen-like 1; CD36 antigen-like 2; CD36L1; CD36L2; Cla1; CLA-1; Collagen type I receptor, thrombospondin receptor-like 1; D5Ertd460e; EPM4; HDL QTL 1; Hdlq1; HDLQTL6; Hlb398; HLGP85; LGP85; LIMP II; LIMP2; LIMP-2; LIMPII; lysosome membrane protein 2; Lysosome membrane protein II; MLGP85; mSR-BI; Scarb1; Scarb2; scavanger receptor class B type 1; scavenger receptor b1; scavenger receptor class B member 1; Scavenger receptor class B member
Host Species
Rabbit
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
Conc. Not Determined
Formulation
whole serum with 0.02% sodium azide
Gene Accession No.
O35114, P27615, P97943, Q14108, Q61009, Q8WTV0
Gene Symbols
SCARB1, SCARB2
Immunogen
Synthetic peptide from the extracellular domain (residues 230-380) of Scavenger Receptor-BI/BII was expressed as two tandem copies in bacteria using the pET system.
Regulatory Status
RUO
Gene ID (Entrez)
117106, 12492, 20778, 25073, 949, 950
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- The PA1-32415 immunogen is: Synthetic peptide from the extracellular domain (residues 230-380) of Scavenger Receptor-BI/BII was expressed as two tandem copies in bacteria using the pET system
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis
- SR-BI and SR-BII (previously known as SR-BI.2) are the alternatively spliced products of a single gene
- SR-BII and SR-BI are identical except for the encoded c-terminal cytoplasmic domain
- Both SR-BI and SR-BII bind HDL and mediates selective uptake of HDL cholesteryl ester, but with SR-BII having an approximately 4-fold lower efficiency than SR-BI
- SR-BI and SR-BII are expressed primarily in liver and non-placental steroidgenic tissues
- Although the role of these scavenger receptors is not completely clear, SR-BII mRNA results from the alternative splicing of SR-BI precursor transcripts with both isoforms mediating selective transfer of lipid between HDL and cells
- Therefore, the relative expression and functional activities of these two isoforms create a potential means of regulating selective lipid transfer between HDL and cells.