PA14269
SPAG5 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA14269-Each-of-1 | In Stock | ₹ 46,502.50 |
PA14269 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
SPAG5
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SPAG5
Gene Alias
AI874642; Astrin; D11Bhm180e; Deepest; hMAP126; MAP126; Mastrin; microtubule-associated protein; mitotic spindle associated protein p126; mitotic spindle coiled-coil related protein; mitotic spindle-associated protein p126; S17; Spag5; sperm associated antigen 5; sperm-associated antigen 5
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10615
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
Q96R06
Gene Symbols
SPAG5
Immunogen
Synthetic peptide: V(532) N Q E S R R A E T L V(543)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- PA1-4269 detects the human MAP126 protein in human samples
- PA1-4269 has been successfully used in Western blot procedures
- PA1-4269 immunizing peptide corresponds to amino acid residues 532-543 of human MAP126 protein
- SPAG5 (sperm associated antigen 5), also known as MAP126, hMAP126, DEEPEST or Astrin, is a 1,193 amino acid protein that is expressed at high levels in testis and at lower levels in liver, placenta, pancreas, colon and thymus
- Localized specifically to spindle poles during prophase and throughout the spindle during metaphase and anaphase, SPAG5 is essential for proper spindle formation and is thought to be involved in the dynamic and functional regulation of mitotic spindles
- Additionally, SPAG5 plays a role in sister chromatid cohesion and subsequent chromatid separation and, via its association with chromatids, is an important regulator of chromosome integrity
- SPAG5 has a long stalk and a globular head domain through which if forms a homodimer that is characterized by aster-like structures
- Upon DNA damage, SPAG5 may be phosphorylated by ATR or ATM.