TIP47 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA146161-Each-of-1 | In Stock | ₹ 48,905.50 |
PA146161 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
TIP47
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PLIN3
Gene Alias
1300012C15Rik; 47 kDa mannose 6-phosphate receptor-binding protein; 47 kDa MPR-binding protein; 47 kDa tail interaction protein; cargo selection protein TIP47; M6prbp1; mannose 6 phosphate receptor binding protein 1; mannose-6-phosphate receptor binding protein 1; mannose-6-phosphate receptor-binding protein 1; MGC11117; MGC2012; perilipin 3; perilipin-3; Placental protein 17; Plin3; PP17; tail-interacting protein, 47 kD; testicular tissue protein Li 114; TIP47; Unknown (protein for MGC:128897)
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10226, 66905
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
tris glycine with 0.15M NaCl and 0.05% sodium azide
Gene Accession No.
O60664, Q9DBG5
Gene Symbols
PLIN3
Immunogen
A synthetic peptide made to a region within the N-terminus (within residues 1-100) of the mouse TIP47 protein
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- In Western Blot analysis, a band is seen ∽47 kDa (isoform B, containing the first 184 residues that isoform A is lacking)
- Suggested positive control: HeLa whole cell lysate and 3T3 L1 lysate
- TIP47 has been described as cargo protein involved in the trafficking of the mannose-6-phosphate receptor between endosomes and the Golgi complex
- Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex
- The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs and is required for endosome to Golgi transport
- This protein also binds directly to the GTPase RAB9, a member of the RAS oncogene family
- The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo
- TIP47 has been localized in milk fat globule membranes of human and bovine origin
- It has been described as a placental protein, as well
- Increased amounts of TIP47 are secreted into circulation of cervix carcinoma patients
- Therefore, this protein is probably significant as an oncodevelopmental marker.