PA146188

TOM70 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA146188-Each-of-1 In Stock ₹ 46,502.50

PA146188 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

TOM70

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TOMM70

Gene Alias

2610044B22Rik; D16Ium22; D16Ium22e; D16Wsu109e; FLJ90470; KIAA0719; Mitochondrial import receptor subunit TOM70; mitochondrial precursor proteins import receptor; mKIAA0719; Tom70; Tomm70; Tomm70a; Translocase of outer membrane 70 kDa subunit; translocase of outer mitochondrial membrane 70; translocase of outer mitochondrial membrane 70 homolog A; translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae); translocase of outer mitochondrial membrane 70 homolog A (yeast); translocase of outer mitochondrial membrane protein 70

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

100352274, 28185, 304017, 9868

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

O94826, Q75Q39, Q9CZW5

Gene Symbols

TOMM70, Tomm70a

Immunogen

Synthetic peptide made to a region within residues 1-100 of the human protein. [Swiss-Prot# O94826].

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rabbit, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Suggested positive control: purified mitochondrial extracts and HeLa whole cell extract
  • Functional mitochondria require up to 1000 proteins to function properly, with 99% synthesized as precursors in the cytoplasm and transported into the mitochondria with the aid of cytosolic chaperones and mitochondrial translocators (import components)
  • Proteins to be imported are chaperoned to the mitochondria by the cytosolic heat shock protein (cHSP70) and are immediately pursued by Translocators of the Outer Membrane (TOMs), followed by transient interactions of the unfolded proteins with Translocators of the Inner Membrane (TIMs)
  • TOMM70A is ubiquitously expressed in human tissues and localizes in the mitochondria
  • TOMM70A could play a significant role in the import of nuclear-encoded mitochondrial proteins with internal targeting sites such as ADP/ATP carriers and the uncoupling proteins.