PA170042

Complement C4b Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA170042-Each-of-1 In Stock ₹ 46,858.50

PA170042 - Each of 1

₹ 46,858.50

In Stock

Quantity

1

Base Price: ₹ 46,858.50

GST (18%): ₹ 8,434.53

Total Price: ₹ 55,293.03

Antigen

Complement C4b

Classification

Polyclonal

Conjugate

Unconjugated

Gene

C4B

Gene Alias

Acidic complement C4; Basic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3; c4 complement; C4A; C4a anaphylatoxin; C4A13; C4A91; C4B; C4B_2; C4B1; C4B12; C4B2; C4B3; C4B5; C4b-A; C4b-B; C4BD; C4d-A; C4d-B; C4F; CH; Chido form of C4; CO4; Complement C4 beta chain; Complement C4 gamma chain; Complement C4-A; Complement C4-A alpha chain; Complement C4-B; Complement C4-B alpha chain; complement C4B1a; complement C4-B-like; complement component 4B (Chido blood group); complement component 4B (Chido blood group), copy 2; CPAMD2; CPAMD3; DADB-112B14.11; FLJ60561; MGC164979

Host Species

Chicken

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

100293534, 721

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Flow Cytometry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

P0C0L5

Gene Symbols

C4B, C4B_2

Immunogen

Purified human complement C4b.

Quantity

500 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgY

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Description

  • PA1-70042 detects C4b in human samples
  • PA1-70042 has been successfully used in flow cytometry, Western blot and ELISA procedures
  • The PA1-70042 immunogen is purified human complement C4b
  • This gene encodes the basic form of complement factor 4, part of the classical activation pathway
  • The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion
  • The trimer provides a surface for interaction between the antigen-antibody complex and other complement components
  • The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation
  • Deficiency of this protein is associated with systemic lupus erythematosus
  • This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6
  • Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene
  • In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9.