c-Fos Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA1830-Each-of-1 | In Stock | ₹ 49,929.00 |
PA1830 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,929.00
GST (18%): ₹ 8,987.22
Total Price: ₹ 58,916.22
Antigen
c-Fos
Classification
Polyclonal
Conjugate
Unconjugated
Gene
FOS
Gene Alias
activator protein 1; AP-1; cellular oncogene c-fos; cellular oncogene fos; cFos; C-FOS; c-fos oncogene; c-fos protooncogene protein; D12Rfj1; FBJ murine osteosarcoma viral (v-fos) oncogene homolog (oncogene FOS); FBJ murine osteosarcoma viral oncogene homolog; FBJ murine osteosarcoma viral oncogene homolog B; FBJ osteosarcoma oncogene; FBJ osteosarcoma oncogene B; FBJ osteosarcoma viral oncogene isoform deltaFosb-2; FOS; Fos proto-oncogene, AP-1 trancription factor subunit; Fos proto-oncogene, AP-1 transcription factor subunit; Fosb; FosB proto-oncogene, AP-1 transcription factor subunit; fra-2; G0/G1 switch regulatory protein 7; G0S7; I79_009428; p55; protein fosB; proto-oncogene cFOS; proto-oncogene c-Fos; proto-oncogene protein c-fos; v-fos FBJ murine osteosarcoma viral oncogene homolog
Host Species
Rabbit
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Gene ID (Entrez)
14281, 2353
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Lyophilized
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
P01100, P01101
Gene Symbols
FOS
Immunogen
Synthetic peptide corresponding to residues S(4) G F N A D Y E A S S S R C(17) of human cFos.
Quantity
200 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- PA1-830 detects cFos from mouse and human cells
- PA1-830 has been successfully used in Western blot and immunofluorescence procedures
- By Western blot, this antibody detects an ∽60 kDa protein representing cFos in NIH 3T3 serum stimulated cells
- The PA1-830 immunogen is a synthetic peptide corresponding to residues S(4) G F N A D Y E A S S S R C(17) of human cFos
- This sequence is completely conserved in mouse cFos
- Reconstitute with 200 μL of PBS (1 mg/mL)
- FBJ murine osteosarcoma viral oncogene homolog is commonly known as Cellular protooncogene Fos (c-Fos)
- It belongs to the fos transcription factor family and is encoded by the C-FOS gene located on chromosome 14
- c-Fos heterodimerizes with c-Jun to form the Activator Protein -1 (AP-1) transcription factor which regulates transcription of several genes that play an important role in cellular signal transduction, cell proliferation and differentiation
- c-Fos has been shown to be phosphorylated by various stimuli including growth factors and insulin at atleast seven different sites
- The best known upstream kinase for phosphorylation at Threonine 232 is ERK MAPK which regulates localization of c-Fos to the nucleus and is thus important for c-Fos induced transcriptional activity.