Placental Alkaline Phosphatase Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA185170-Each-of-1 | In Stock | ₹ 46,502.50 |
PA185170 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Placental Alkaline Phosphatase
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ALPP
Gene Alias
Alkaline phosphatase placental type; Alkaline phosphatase Regan isozyme; alkaline phosphatase, placental; alkaline phosphatase, placental type; alkaline phosphomonoesterase; ALP; Alp1; ALPP; AP-TNAP; DOA1; FLJ11281; FLJ40094; FLJ61142; FLJ93059; Germ-cell alkaline phosphatase; glycerophosphatase; HOPS; MGC161443; MGC167935; nagao Isozyme; P PLAP; PALP; PLA2P; PLAA; placental alkaline phosphatase 1; placental heat-stable alkaline phosphatase; PLAP; PLAP1; PLAP-1; rCG23846-like; Regan isozyme; TNAP; TNSALP
Host Species
Sheep
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
250
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Immunomicroscopy, Western Blot
Concentration
5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P05187
Gene Symbols
ALPP
Immunogen
Purified alkaline phosphatatse from human placenta.
Quantity
1 mL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody has been found to be reactive with both placental and bone AP
- Sheep anti Human Alkaline Phosphatase antibody recognizes alkaline phosphatase, it has been found to be reactive with both placental and bone alkaline phosphatase
- Placental Alkaline Phosphatase plays an important role in the regulation of specific inflammatory disease processes
- There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney for this form of alkaline phosphatase have been well characterized
- Placental Alkaline Phosphatase reacts with a membrane-bound isoenzyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation
- Placental Alkaline Phosphatase is useful in the identification of testicular germ cell tumors
- Unlike germ cell tumors, PLAP-positive somatic cell tumors uniformly express epithelial membrane antigen (EMA)
- A proposed function of Placental Alkaline Phosphatase is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development
- Placental Alkaline Phosphatase has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects
- The character of hypophosphatasia can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms.