PA185347
Cortisol Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA185347-Each-of-1 | In Stock | ₹ 42,408.50 |
PA185347 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,408.50
GST (18%): ₹ 7,633.53
Total Price: ₹ 50,042.03
Antigen
Cortisol
Classification
Polyclonal
Conjugate
Unconjugated
Host Species
Sheep
Purification Method
Affinity chromatography
Regulatory Status
RUO
Target Species
Chemical
Product Type
Antibody
Isotype
IgG
Applications
ELISA
Concentration
5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Immunogen
Cortisol-21-hemisuccinyl-KLH/BSA/Fetuin mixture.
Quantity
1 mL
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Target Molecule
Chemical
Related Products
Description
- PA1-85347 detects Cortisol
- The following cross-reactivities have been observed: Cortisol-100%, Corticosterone- >90%
- Sheep anti cortisol antibody recognizes the glucocorticoid hormone cortisol, produced in the adrenal cortex and involved in responses to stress
- Observed cross reactivities include: Cortisol 100%, Corticosterone >90%
- Cortisol is the most potent glucocorticoid produced by the human adrenal
- It is synthesized from cholesterol and its production is stimulated by pituitary adrenocorticotropic hormone (ACTH) which is regulated by corticotropin releasing factor (CRF)
- ACTH and CRF secretions are inhibited by high cortisol levels in a negative feedback loop
- In plasma a majority of cortisol is bound with high affinity to corticosteroid binding globulin (CBG or transcotin)
- Cortisol acts through specific intracellular receptors and affects numerous physiologic systems including immune function, glucose counter regulation, vascular tone, and bone metabolism.