DUSP2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA3115-Each-of-1 | In Stock | ₹ 47,926.50 |
PA3115 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,926.50
GST (18%): ₹ 8,626.77
Total Price: ₹ 56,553.27
Antigen
DUSP2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DUSP2
Gene Alias
dual specificity phosphatase 2; dual specificity protein phosphatase 2; Dual specificity protein phosphatase PAC-1; dual-specificity phosphatase 2; Dusp2; PAC1; Pac-1; serine/threonine specific protein phosphatase
Host Species
Rabbit
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
Conc. Not Determined
Formulation
whole serum with 0.05% sodium azide
Gene Accession No.
Q05922, Q05923
Gene Symbols
DUSP2
Immunogen
Synthetic peptide, KLH conjugated, corresponding to the residues L(506) S K S S S Q I R M S G L P A D N L A T(525) of human PAC1.
Regulatory Status
RUO
Gene ID (Entrez)
13537, 1844
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- PA3-115 detects PAC1 in human samples
- PA3-115 has been successfully used in Western blot, immunocytochemistry and immunohistochemistry procedures
- By Western blot, this antibody detects an ∽40-60 kDa protein representing PAC1 in human samples
- In immunohistochemistry, PAC1 immunoreactivity is predominantly localized to the plasma membrane
- PA3-115 immunogen is a synthetic peptide, KLH conjugated, corresponding to the residues L(506) S K S S S Q I R M S G L P A D N L A T(525) of human VPAC2 receptor
- The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily
- These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues
- They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation
- Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli
- This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus.