PA540097
5-hydroxymethylcytosine Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA540097-Each-of-1 | In Stock | ₹ 52,332.00 |
PA540097 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,332.00
GST (18%): ₹ 9,419.76
Total Price: ₹ 61,751.76
Antigen
5-hydroxymethylcytosine
Classification
Polyclonal
Conjugate
Unconjugated
Gene Alias
5hmc; 5-hmc; 5-HydroxymethylCytidine; C5H7N3O2
Immunogen
Human KLH-conjugated 5-hydroxymethylcytosine.
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
-20°C or -80°C if preferred
Form
Liquid
Applications
ELISA, Immunoprecipitation, Peptide Array
Concentration
3.5 mg/mL
Formulation
PBS with 0.05% ProClin 300, 0.05% sodium azide; pH 7.4
Host Species
Rabbit
Purification Method
Protein G
Regulatory Status
RUO
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- 5-hydroxymethylcytosine (5-hmC) has been recently discovered in mammalian DNA
- 5-hmC results from the enzymatic conversion of 5-methylcytosine into 5-hydroxymethylcytosine by the TET family of oxygenases
- Initially, the 5-hmC base had been identified in Purkinje neurons, in granule cells and embryonic stem cells where it is present at high levels (up to 0,6% of total nucleotides in Purkinje cells)
- A recent report indicates that 5-hmC is also abundant in brain tissue, especially in areas that are associated with higher cognitive functions.Early evidence suggests that 5-hmC may represent an intermediate in a new pathway which demethylates DNA, converting 5-mC to cytosine
- Although its precise role has still to be shown, recent results indicate, however, that 5-hmC may play important roles distinct from 5-mC
- This may open up entirely new perspectives in epigenetic studies.