PCID2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA540118-Each-of-1 | In Stock | ₹ 45,968.50 |
PA540118 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,968.50
GST (18%): ₹ 8,274.33
Total Price: ₹ 54,242.83
Antigen
PCID2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PCID2
Gene Alias
A730042J05Rik; CSN12-like protein; F10; fa11f03; HT004; hypothetical protein LOC617943; ik:tdsubc_1e10; im:6909928; PCI domain containing 2; PCI domain-containing protein 2; Pcid2; RGD1307041; RP11-98F14.6; tdsubc_1e10; wu:fa11f03; xx:tdsubc_1e10; zgc:101845
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
55795
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 20% glycerol and 0.01% Thimerosal; pH 7
Gene Accession No.
Q5JVF3
Gene Symbols
PCID2
Immunogen
Recombinant protein encompassing a sequence within the center region of human PCID2.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: HCT116 cells
- Predicted reactivity: Mouse (94%), Rat (94%), Zebrafish (83%), Xenopus laevis (91%), Chicken (94%), Chimpanzee (100%), Bovine (89%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation
- Component of the TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, DSS1, and either centrin CETN2 or CETN3 (PubMed:22307388)
- The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket)
- TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery
- Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and transcription-associated genomic instability
- R-loop accumulation does not increase in PCID2-depleted cells.