PA548475
COCH Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA548475-Each-of-1 | In Stock | ₹ 47,036.50 |
PA548475 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,036.50
GST (18%): ₹ 8,466.57
Total Price: ₹ 55,503.07
Antigen
COCH
Classification
Polyclonal
Conjugate
Unconjugated
Gene
COCH
Gene Alias
AW122937; coagulation factor C homolog (Limulus polyphemus); coagulation factor C homolog, cochlin (Limulus polyphemus); Coch; COCH5B2; COCH-5B2; Cochlin; D12H14S564E; DFNA9; PRO294; UNQ257; UNQ257/PRO294
Host Species
Rabbit
Purification Method
Antigen affinity chromatography, Protein A
Regulatory Status
RUO
Gene ID (Entrez)
1690
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
O43405
Gene Symbols
COCH
Immunogen
KLH conjugated synthetic peptide between 399-428 amino acids from the Central region of human COCH.
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Predicted to react with bovine based on sequence homology
- Cochlin is a secreted protein encoded by the coagulation factor C homology (COCH) gene, a cochlear gene
- It constitutes 70% of the inner ear proteins and is classified into three glycosylated isoforms: p63s, p44s and p40
- Cochlin contains an N-terminal LCCL domain and two von Willebrand factor A-like domains
- Mutations in the COCH gene cause DFNA9, an autosomal dominant nonsyndromic auditory and vestibular dysfunction disorder, as a result of either an amino acid deletion in the LCCL domain or missense substitutions
- Microfibrillar deposits accumulate in the inner ear of individuals with DFNA9 and these deposits may contain the Cochlin protein
- Cochlin is a target antigen for autoimmune sensorineural hearing loss.