TIAM2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA548604-Each-of-1 | In Stock | ₹ 46,502.50 |
PA548604 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
TIAM2
Classification
Polyclonal
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
Q6ZPF3, Q8IVF5
Gene Symbols
Tiam2
Immunogen
KLH conjugated synthetic peptide between 357-385 amino acids from the N-terminal region of human TIAM2.
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Conjugate
Unconjugated
Gene
Tiam2
Gene Alias
3000002F19Rik; KIAA2016; mKIAA2016; RAS-related C3 botulinum substrate 1, guanine nucleotide exchange factor 1; SIF and TIAM1-like exchange factor; Stef; T cell lymphoma invasion and metastasis 2; T-cell lymphoma invasion and metastasis 2; T-cell lymphoma invasion and metastasis 2; RAS-related C3 botulinum substrate 1, guanine nucleotide exchange factor 1; TIAM2; TIAM-2; T-lymphoma invasion and metastasis-inducing protein 2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography, Protein A
Regulatory Status
RUO
Gene ID (Entrez)
24001, 26230
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
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Description
- Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities
- Acts as a GDP- dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them
- Mediates extracellular laminin signals to activate Rac1, contributing to neurite growth
- Involved in lamellipodial formation and advancement of the growth cone of embryonic hippocampal neurons
- Promotes migration of neurons in the cerebral cortex
- When overexpressed, induces membrane ruffling accompanied by the accumulation of actin filaments along the altered plasma membrane
- Activates specifically RAC1, but not CDC42 and RHOA.