PA549723

MCMBP Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA549723-Each-of-1 In Stock ₹ 46,502.50

PA549723 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

MCMBP

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MCMBP

Gene Alias

1110007A13Rik; AU017382; BC025641; C10orf119; cj119; MCM (minichromosome maintenance deficient) binding protein; MCM-binding protein; Mcmbp; MCM-BP; minichromosome maintenance complex binding protein; Mini-chromosome maintenance complex-binding protein; minichromosome maintenance complex-binding protein; RGD1306730

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

309009, 79892

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

B1H268, Q9BTE3

Gene Symbols

MCMBP

Immunogen

Synthetic peptide peptide corresponding to a region derived from 176-190 amino acids of human minichromosome maintenance complex binding protein

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous level of total MCMBP protein
  • MEK1 (Mitogen activated protein kinase kinase 1) catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases
  • MEK1 activates ERK1 and ERK2 MAP kinases
  • Mitogen activated protein kinase kinase 2 (MEK2 or MAPKK2) is a member of a family of tyrosine/threonine protein kinases that activate the ERK1 and 2 and MAPK enzymes by phosphorylating both residues within the threonine/glutamate/tyrosine (TEY) motif in the activation loop
  • MEK1 and 2 are also activated by dual phosphorylation, which occurs on serine 218 and 222, in the activation loop of the MEK
  • Threonine 292 of MEK1 is phosphorylated by ERK 2, which serves as a negative feedback loop by suppressing activation of MEK1.