PA549772

KIP2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA549772-Each-of-1 In Stock ₹ 46,502.50

PA549772 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

KIP2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CIB2

Gene Alias

2810434I23Rik; AI449053; calcium and integrin binding family member 2; calcium and integrin-binding family member 2; calcium binding protein Kip 2; calcium binding protein Kip2; CIB2; DFNB48; DNA-dependent protein kinase catalytic subunit-interacting protein 2; kinase interacting protein 2; kinase-interacting protein 2; KIP 2; Kip2; USH1J

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10518, 56506

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O75838, Q9Z309

Gene Symbols

CIB2

Immunogen

Synthesized peptide derived from internal of human CIB2.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total KIP2 protein
  • DNA-dependent protein kinases (DNA-PK) play a role in the repair of double-strand DNA breaks and in the process of V(D)J recombination during lymphoid development
  • By EST database searching for sequences homologous to the DNA-PK gene KIP/CIB and 5-prime RACE, Seki, N et al
  • isolated a full-length cDNA, which they designated as KIP2, from a human fetal brain cDNA library
  • KIP2 encodes a deduced 187-amino acid protein with a predicted molecular mass of 22 kD
  • The KIP2 protein shares 46%, 39%, and 30% sequence identity with the calcium-binding proteins KIP/CIB, calcineurin B and calmodulin respectively
  • KIP2 contains two EF-hand motifs and a helix-loop-helix motif involved in coordinating the calcium ion, indicating that KIP2 may also bind calcium
  • KIP2 is ubiquitously expressed in various human tissues.