PA550172

NDFIP1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA550172-Each-of-1 In Stock ₹ 46,502.50

PA550172 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

NDFIP1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NDFIP1

Gene Alias

0610010M22Rik; Breast cancer-associated protein SGA-1M; N4wbp5; Ndfip1; Nedd4 family interacting protein 1; NEDD4 family-interacting protein 1; Nedd4 WW binding protein 5; NEDD4 WW domain-binding protein 5; Nedd4 WW-binding protein 5; PSEC0192; PSEC0223; Putative MAPK-activating protein PM13; putative NF-kappa-B-activating protein 164; Putative NFKB and MAPK-activating protein

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

291609, 65113, 80762

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q5U2S1, Q8R0W6, Q9BT67

Gene Symbols

NDFIP1

Immunogen

Synthesized peptide derived from C-terminal of human NDFIP1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total NDFIP1 protein
  • The NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein
  • It is a potential target for ubiquitination by the Nedd4 family of proteins
  • NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neuronal survival
  • NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEN/Akt signaling pathways
  • Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.