TRAF4 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA550176-Each-of-1 | In Stock | ₹ 46,502.50 |
PA550176 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
TRAF4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TRAF4
Gene Alias
A530032M13Rik; Cart1; cysteine-rich domain associated with ring and TRAF domain; cysteine-rich domain associated with RING and Traf domains protein 1; Cysteine-rich motif associated to RING and Traf domains protein 1; malignant 62; metastatic lymph node gene 62 protein; MLN 62; MLN62; msp2; RING finger protein 83; RNF83; RNF83malignant 62; TNF receptor associated factor 4; TNF receptor-associated factor 4; tnf receptor-associated factor 4b; traf4; TRAF4 protein; TRAF4 variant 6; traf4b; tumor necrosis receptor-associated factor 4A
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22032, 9618
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q61382, Q9BUZ4
Gene Symbols
TRAF4
Immunogen
Synthesized peptide derived from internal of human TRAF4.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The antibody detects endogenous levels of total TRAF4 protein
- The tumor necrosis factor (TNF) receptor superfamily is composed of several type I integral membrane glycoproteins that exhibit homology in their cystine rich extracellular domains
- Members of this family include TNF-RI, TNF-RII and CD40
- Ligands for these receptors can be small, secreted proteins, such as TNF, or type II integral membrane proteins, as is the case for the CD40 ligand, CD40L
- While the signal transduction mechanism of the TNF receptor superfamily is poorly understood, activation of TNF-R or CD40 have been shown to induce the nuclear translocation of NFkB
- Members of the TRAF (TNF receptor-associated factor) family have been implicated in this process
- Four members have thus far been described and are designated TRAF1, TRAF2, TRAF3 (variously referred to as CRAF1, LAP1 or CD40bp) and TRAF4
- TRAF4, originally termed CART1, is specifically expressed in breast carcinomas, and is localized to the nucleus in such tissues.