KLF15 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA550232-Each-of-1 | In Stock | ₹ 46,502.50 |
PA550232 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
KLF15
Classification
Polyclonal
Conjugate
Unconjugated
Gene
KLF15
Gene Alias
1810013I09Rik; AV048136; AW494632; Cardiovascular Krueppel-like factor; CKLF; DKFZp779M1320; Kidney-enriched krueppel-like factor; kidney-enriched Kruppel-like factor; KKLF; KKLF protein; Klf15; KLF15; transcription factor; Krueppel-like factor 15; Kruppel like factor 15; Kruppel-like factor 15
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
28999
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Concentration
1.3 mg/mL
Formulation
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
Q9UIH9
Gene Symbols
KLF15
Immunogen
Fusion protein corresponding to residues near the N terminal of human Kruppel-like factor 15
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The antibody detects endogenous levels of total KLF15 protein
- KLF15 is a nuclear protein belonging to the Sp1 C2H2-type zinc-finger protein family with three C2H2-type zinc fingers
- A transcriptional activator, KLF15 binds to the GA element of the CLCNKA promoter and may help to regulate the strict tissue and nephron segment-specific expression of CLCNKA and CLCNKB channel genes
- It plays an essential role in adipogenesis in cells through its regulation of PPARG expression
- Reports suggest that KLF15 is an inhibitor of cardiac hypertrophy and functions in a pathway, regulating the cardiac response to hemodynamic stress, and regulates mitochondrial acetyl-CoA synthase expression in skeletal muscle
- KLF15 may also act as a transcriptional repressor of the rhodopsin and IRBP promoters in the retina, and is a possible participant in repression of photoreceptor-specific gene expression in nonphotoreceptor cells
- It is highly expressed in liver, followed by heart, skeletal muscle, and kidney but not expressed in bone marrow or lymphoid tissues.