SPDL1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA550267-Each-of-1 | In Stock | ₹ 46,502.50 |
PA550267 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
SPDL1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SPDL1
Gene Alias
1700018I02Rik; 2600001J17Rik; 2810049B11Rik; AA409762; arsenite-related gene 1 protein; Ccdc99; coiled-coil domain containing 99; coiled-coil domain-containing protein 99; coiled-coil domain-containing protein 99 {ECO:0000255; HAMAP-Rule:MF_03041}; hSpindly; protein Spindly; RGD1306908; Rhabdomyosarcoma antigen MU-RMS-40.4A; rrhabdomyosarcoma antigen protein MU-RMS-40.4A; SPDL1; Spindle apparatus coiled-coil domain-containing protein 1; spindle apparatus coiled-coil domain-containing protein 1 {ECO:0000255; spindle apparatus coiled-coil protein 1; spindly homolog
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
54908, 70385
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
0.8 mg/mL
Formulation
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
Q923A2, Q96EA4
Gene Symbols
SPDL1
Immunogen
Fusion protein corresponding to residues near the C terminal of human Spindle apparatus coiled-coil protein 1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The antibody detects endogenous levels of total CCDC99 / SPDL1 protein
- The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions
- Differential and in situ hybridizations indicate that this lectin is specifically expressed in keratinocytes
- It is expressed at all stages of epidermal differentiation (i.e., in basal and suprabasal layers)
- The protein was found mainly in stratified squamous epithelium
- It is moderately repressed by retinoic acid
- The antigen localized to basal keratinocytes, although it was also found at lower levels in the suprabasal layers, where it concentrated to areas of cell-to-cell contact
- The cellular localization and its striking down-regulation in cultured keratinocytes imply a role in cell-cell and/or cell-matrix interactions necessary for normal growth control.