PA550276
TFF2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA550276-Each-of-1 | In Stock | ₹ 46,502.50 |
PA550276 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
TFF2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Tff2
Gene Alias
mSP; pancreatic spasmolytic polypeptide; PSP; SML1; SP; spasmolysin; Spasmolytic polypeptide; spasmolytic protein 1; Tff2; Trefoil factor 2; trefoil factor 2 (spasmolytic protein 1)
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
7032
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Concentration
1.2 mg/mL
Formulation
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
Q03403
Gene Symbols
Tff2
Immunogen
Fusion protein corresponding to a region derived from internal residues of human trefoil factor 2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The antibody detects endogenous levels of total SP / TFF2 protein
- Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing and protection of the gastrointestinal epithelia
- These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain
- SP (spasmolytic polypeptide), also designated Trefoil factor 2 (TFF2) precursor, is a trefoil protein that functions to inhibit gastrointestinal motility and gastric acid secretion
- SP may also act as a structural component of the gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains
- A downregulation of SP expression is associated with primary gastric cancer, and a progressive loss of this protein is likely to be involved in the early stage of the multi-step gastric carcinogenesis pathway.