PA550286

AADACL2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA550286-Each-of-1 In Stock ₹ 46,502.50

PA550286 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

AADACL2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

AADACL2

Gene Alias

Aadacl2; ADCL2; arylacetamide deacetylase like 2; arylacetamide deacetylase-like 2; EG639634; MGC72001; RGD1563197

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

344752

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1.1 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q6P093

Gene Symbols

AADACL2

Immunogen

Fusion protein corresponding to residues near the C terminal of human arylacetamide deacetylase-like 2

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PA550322

--

Img

Thermo Scientific

PA550330

--

Img

Thermo Scientific

PA550285

--

Img

Thermo Scientific

PA550301

--

Img

Thermo Scientific

PA550321

--

Img

Thermo Scientific

PA550465

--

Img

Thermo Scientific

PA550378

--

Img

Thermo Scientific

PA550874

--

Description

  • The antibody detects endogenous levels of total AADACL2 protein
  • AADAC is a 45 kDa membrane-associated hydrolase highly expressed in the human liver that has been implicated in the hydrolysis of arylacetamide xenobiotics including flutamide and phenacetin.556-560AADAC is highly homologous to several related lipases, AADACL1, 2, and 4, the latter two of which remain completely unannotated
  • Overexpression of AADAC in a rat hepatoma cell line produces changes in cellular TG levels, apoplipoprotein B secretion, and fatty acid oxidation, but the mechanism for these effects remains unclear
  • 561 Candidate endogenous substrates, selective inhibitors, or knockout mice have not, to our knowledge, been described for AADAC or the related enzymes AADACL2 and AADACL4.