ABH1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA550290-Each-of-1 | In Stock | ₹ 46,502.50 |
PA550290 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
ABH1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ALKBH1
Gene Alias
2700073G19Rik; Abh; ABH1; alkB; alkB homolog 1, histone H2A dioxygenase; alkB, alkylation repair homolog 1; alkB, alkylation repair homolog 1 (E. coli); ALKBH; Alkbh1; Alkylated DNA repair protein alkB homolog 1; alkylation repair, alkB homolog; alpha-ketoglutarate-dependent dioxygenase ABH1; DNA 6mA demethylase; DNA demethylase ALKBH1; DNA lyase ABH1; DNA N6-methyl adenine demethylase; DNA N6-methyl adenine demethylase ALKBH1; DNA oxidative demethylase ALKBH1; hABH; mRNA N(3)-methylcytidine demethylase; Nucleic acid dioxygenase ALKBH1; tRNA N1-methyl adenine demethylase
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
211064, 8846
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
P0CB42, Q13686
Gene Symbols
ALKBH1
Immunogen
Fusion protein corresponding to residues near the N terminal of human AlkB, alkylation repair homolog 1 (E. coli)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The antibody detects endogenous levels of total ALKBH1 protein
- This gene encodes a homolog to the E
- coli alkB gene product
- The E
- coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair
- It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine
- Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation
- Requires molecular oxygen, alpha-ketoglutarate and iron
- May have a role in placental trophoblast lineage differentiation
- Has DNA lyase activity and introduces double-stranded breaks at abasic sites
- Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites.