CARF Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA550320-Each-of-1 | In Stock | ₹ 46,502.50 |
PA550320 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
CARF
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CARF
Gene Alias
Als2cr8; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8; amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein; amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein homolog; calcium response factor; calcium responsive transcription factor; calcium-response factor; calcium-response factor CaRF; calcium-responsive transcription factor; CaRF; ECBRC-FC1; ECBRC-FC2; NYD-SP24; testis development protein NYD-SP24
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
79800
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
1.2 mg/mL
Formulation
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
Q8N187
Gene Symbols
CARF
Immunogen
Fusion protein corresponding to residues near the C terminal of human calcium responsive transcription factor
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The antibody detects endogenous levels of total CARF / ALS2CR8 protein
- CARF (calcium-response factor), also known as ALS2CR8 (amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein) or NYD-SP24, is a 725 amino acid nuclear protein
- Expressed in a wide variety of tissues with highest expression in the hippocampus, CARF is thought to be a transcription factor that associates with the p53 tumor suppression pathway
- CARF cooperates, co-localizes and is co-regulated with ARF, an ADP-ribosylation factor, and, through this interaction, helps to mediate ARF-p53-induced apoptotic signaling
- This apoptotic pathway is implicated in cell cycle control, proper cellular development, response to DNA damage and the aging process, suggesting that CARF participates in various events throughout the cell.