PA550435

KIF1C Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA550435-Each-of-1 In Stock ₹ 46,502.50

PA550435 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

KIF1C

Classification

Polyclonal

Conjugate

Unconjugated

Gene

KIF1C

Gene Alias

B430105J22Rik; D11Bwg1349e; KIAA0706; Kif1c; Kif1d; kinesin 1C; kinesin family member 1C; kinesin superfamily protein 1C; kinesin-like protein KIF1C; Kinesin-like protein KIF1D; lethal factor toxin susceptibility 1; Ltxs1; N-3 kinsin; SATX2; SAX2; spastic ataxia 2 (autosomal recessive); SPAX2; SPG58

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10749

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

2.7 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

O43896

Gene Symbols

KIF1C

Immunogen

Fusion protein corresponding to a region derived from internal residues of human kinesin family member 1C

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total KIF1C protein
  • The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell
  • Individual kinesin members play crucial roles in cell division, intracellular transport, and membrane trafficking events including endocytosis and transcytosis
  • KIF1C is a member of the KIF1/Unc104 family of kinesin-like proteins, which are involved in the transport of mitochondria or synaptic vesicles in axons
  • Human KIF1C maps to chromosome 17p13 and encodes a predicted 1,103 amino acid protein with abundant expression in heart and skeletal muscle
  • Tyrosine phosphorylation is a putative regulator of KIF1C mediated retrograde transport of Golgi vesicles to the endoplasmic reticulum
  • KIF1C is capable of forming homodimers and can noncovalently associate with 14-3-3 beta, gamma, epsilon and zeta
  • In mouse macrophages, KIF1C is required for anthrax lethal toxin resistance.