PA550536

MRP7 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA550536-Each-of-1 In Stock ₹ 48,104.50

PA550536 - Each of 1

₹ 48,104.50

In Stock

Quantity

1

Base Price: ₹ 48,104.50

GST (18%): ₹ 8,658.81

Total Price: ₹ 56,763.31

Antigen

MRP7

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ABCC10

Gene Alias

ABCC10; ATP binding cassette subfamily C member 10; ATP-binding cassette sub-family C member 10; ATP-binding cassette, subfamily C (CFTR/MRP), member 10; ATP-binding cassette, sub-family C (CFTR/MRP), member 10; EST182763; mFLJ00002; Mrp7; Multidrug resistance-associated protein 7; SIMRP7

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

89845

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1.1 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q5T3U5

Gene Symbols

ABCC10

Immunogen

Synthetic peptide corresponding to a region derived from internal residues of human ATP-binding cassette, sub-family C (CFTR/MRP), member 10

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total ABCC10 protein
  • The MRP family is represented by nine similar ABC transporters that have the ability to transport structurally diverse lipophilic anions and operate as chemical efflux pumps
  • MRP7 (multidrug resistance-associated protein 7, ATPbinding cassette sub-family C member 10) is a multi-pass membrane protein that belongs to the ABC transporter family (conjugate transporter subfamily)
  • MRP7 is involved with the ATP-dependent transport of 17β-estradiol-D-17-β-glucuronide (E217βG)
  • MRP7 is also probably involved in cellular detoxification through its lipophilic anion extrusion capabilities
  • MRP7 contains two ABC transmembrane type 1 domains and two ABC transporter domains
  • MRP7 likely has three isoforms
  • Isoform 2 is the most widely expressed, while isoform 1 is predominately expressed in the spleen.