SLC8A2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA550558-Each-of-1 | In Stock | ₹ 46,502.50 |
PA550558 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
SLC8A2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Slc8a2
Gene Alias
KIAA1087; Na(+)/Ca(2+)-exchange protein 2; Na+/Ca2+-exchanging protein Nac2; NCX2; Slc8a2; sodium/calcium exchanger 2; sodium-calcium exchanger 2; solute carrier family 8 (sodium/calcium exchanger), member 2; solute carrier family 8 (sodium-calcium exchanger), member 2; solute carrier family 8 member 2; solute carrier family 8 member A2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
6543
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Concentration
0.4 mg/mL
Formulation
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
Q9UPR5
Gene Symbols
Slc8a2
Immunogen
Synthetic peptide corresponding to a region derived from internal residues of human solute carrier family 8 (sodium/calcium exchanger), member 2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The antibody detects endogenous levels of total SLC8A2 protein
- Sodium/calcium exchanger proteins are integral membrane proteins primarily seen in cardiac cells
- In cardiac myocytes, the concentration of Ca2+ alternates between low levels during relaxation and high levels during contraction
- The Na+/Ca2+ exchanger 1 (NCX1) protein mediates Ca2+ extrusion from cardiac cells during relaxation
- Four NCX1 isoforms (NCX1.1, NCX1.3, NCX1.7, and NCX1.10) result from alternate splicing
- NCX1 mRNA is present at high levels in the heart, with lower levels present in the brain
- NCX2 is most abundantly expressed in brain, in contrast the the broader distribution of NCX1, which is also expressed in heart, kidney, lung, smooth and skeletal muscle
- The difference in expression for the transporter subtypes is believed to reflect differences in their functional roles
- Regulation mechanisms for these exchanger proteins have not been fully characterized.