PA550589

FZD8 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA550589-Each-of-1 In Stock ₹ 46,502.50

PA550589 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

FZD8

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Fzd8

Gene Alias

frizzled 8, seven transmembrane spanning receptor; frizzled class receptor 8; frizzled family receptor 8; frizzled homolog 8; frizzled homolog 8 (Drosophila); frizzled-8; Fz8; Fz-8; Fzd8; hFZ8; HGNC:4046

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14370, 364754, 8325

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1.1 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q498S8, Q61091, Q9H461

Gene Symbols

Fzd8

Immunogen

Synthetic peptide corresponding to residues near the C terminal of human frizzled family receptor 8

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total FZD8 / Frizzled 8 protein
  • Members of the Frizzled family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins
  • Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway
  • Frizzled 8 is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer
  • Its expression has been reported in brain, heart, kidney, pancreas, and skeletal muscle
  • ESTs have been isolated from embryo, eye, head/neck, heart, kidney, liver/spleen, pancreas, prostate, and testis libraries, as well as many tumor libraries
  • The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.