PA550624

SLC6A4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA550624-Each-of-1 In Stock ₹ 46,057.50

PA550624 - Each of 1

₹ 46,057.50

In Stock

Quantity

1

Base Price: ₹ 46,057.50

GST (18%): ₹ 8,290.35

Total Price: ₹ 54,347.85

Antigen

SLC6A4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SLC6A4

Gene Alias

5 OCD1, 5HT transporter, 5HTT, 5-HTT, 5-HTTLPR, 5-hydroxytryptamine (serotonin) transporter, AI323329, HGNC:11050, hSERT, HTT, Na+/Cl- dependent serotonin transporter, OCD1, OTTHUMP00000163633, serotonin transporter, serotonin transporter 1, Sert, SERT1, Slc6a4, Sodium-dependent serotonin transporter, Sodium-dependent serotonin transporter (5HT transporter) (5HTT), solute carrier family 6 (neurotransmitter transporter serotonin) member 4 (5-hydroxytryptamine (serotonin) transporter), Solute carrier family 6 (neurotransmitter transporter serotonin) member 4 (5-hydroxytryptamine (serotonin) transporter), solute carrier family 6 (neurotransmitter transporter), member 4, solute carrier family 6 (neurotransmitter transporter, serotonin), member 4, solute carrier family 6 member 4, solute carrier family 6, member 4

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

15567, 25553, 6532

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

0.2 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

P31645, P31652, Q60857

Gene Symbols

SLC6A4

Immunogen

Synthetic peptide corresponding to a region derived from internal residues of human solute carrier family 6 (neurotransmitter transporter), member 4

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total SLC6A4 / 5-HTT protein
  • SERT is an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons
  • The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner
  • This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family
  • A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.