PA550643

CRIM1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA550643-Each-of-1 In Stock ₹ 46,502.50

PA550643 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

CRIM1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CRIM1

Gene Alias

AU015004; Crim1; CRIM-1; cysteine rich transmembrane BMP regulator 1; cysteine rich transmembrane BMP regulator 1 (chordin like); cysteine rich transmembrane BMP regulator 1 (chordin-like); cysteine-rich motor neuron 1; cysteine-rich motor neuron 1 protein; Cysteine-rich repeat-containing protein S52; Processed cysteine-rich motor neuron 1 protein; S52; UNQ1886/PRO4330

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

51232

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1.5 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q9NZV1

Gene Symbols

CRIM1

Immunogen

Synthetic peptide corresponding to a region derived from internal residues of human cysteine rich transmembrane BMP regulator 1 (chordin-like)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total CRIM1 protein
  • CRIM1 (cysteine-rich motor neuron 1), a glycosylated type I transmembrane protein, plays a role in tissue development i.e
  • capillary formation and maintenance during angiogenesis
  • It contains an N-terminal IGF-binding protein-like motif and six von Willebrand-like cysteine-rich repeats (CRRs) in its extracellular domain
  • CRIM1 interacts with BMP4 and BMP7 via the CRRs and functions as an antagonist
  • CRIM1 is developmentally expressed in a number of tissues including the pancreas, kidney, placenta, brain and blood vessels
  • CRIM1 may participate in CNS and placental development by interacting with growth factors involved in motor neuron differentiation and survival.