PA550711
MT-ND3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA550711-Each-of-1 | In Stock | ₹ 46,502.50 |
PA550711 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
MT-ND3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MT-ND3
Gene Alias
1.6.5.3; mitochondrially encoded NADH dehydrogenase 3; Mtnd3; mt-Nd3; NADH dehydrogenase subunit 3; NADH3; NADH-ubiquinone oxidoreductase chain 3; ND3
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4537
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Concentration
1.5 mg/mL
Formulation
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
P03897
Gene Symbols
MT-ND3
Immunogen
Synthetic peptide corresponding to a region derived from internal residues of human mitochondrially encoded NADH dehydrogenase 3
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The antibody detects endogenous levels of total MT-ND3 protein
- NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane
- Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by trans-location of protons from the mitochondrial matrix to the intermembrane space
- Human complex I appears to consist of 41 subunits
- A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm
- NADH dehydrogenase subunit 3 (ND3) localizes to the hydrophobic protein fragment of complex I
- Mutations in the gene encodiing for ND3 may be associated with Parkinson disease.