PA550738

PUS10 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA550738-Each-of-1 In Stock ₹ 46,502.50

PA550738 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

PUS10

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Pus10

Gene Alias

2810013G11Rik; 4933435A13Rik; AU014648; C77560; CCDC139; coiled-coil domain containing 139; coiled-coil domain-containing protein 139; DOBI; pseudouridine synthase 10; pseudouridylate synthase 10; psi55 synthase; Pus10; Putative tRNA pseudouridine synthase Pus10; RGD1306402; tRNA pseudouridine 55 synthase; tRNA pseudouridylate synthase; tRNA-uridine isomerase

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

150962, 74467

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

2.8 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q3MIT2, Q9D3U0

Gene Symbols

Pus10

Immunogen

Synthetic peptide corresponding to a region derived from internal residues of human pseudouridylate synthase 10

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total PUS10 protein
  • Pseudouridylate synthases catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs
  • PUS10 catalyzes the formation of the universal psi55 in the GC loop of transfer RNAs (Probable)
  • Modulator of TRAIL-induced cell death via activation of procaspase 8 and BID cleavage
  • Required for the progression of the apoptotic signal through intrinsic mitochondrial cell death.