PA550752

SEPN1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA550752-Each-of-1 In Stock ₹ 46,502.50

PA550752 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

SEPN1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SELENON

Gene Alias

1110019I12Rik; AI414492; cb686; CFTD; FLJ24021; MDRS1; RSMD1; RSS; selenon; Selenoprotein N; selenoprotein N, 1; SELN; SePN; sepn1; wu:fb06g01; wu:fb73d02; wu:fv41b08; zgc:101091

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

57190

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

0.5 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q9NZV5

Gene Symbols

SELENON

Immunogen

Synthetic peptide corresponding to a region derived from internal residues of human selenoprotein N, 1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total SEPN1 protein
  • SEPN1 is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site
  • Mutations in SEPN1 gene cause the classical phenotype of multiminicore disease and congenital muscular dystrophy with spinal rigidity and restrictive respiratory syndrome
  • This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site
  • The selenocysteine is encoded by the UGA codon that normally signals translation termination
  • The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal
  • Mutations in this gene cause the classical phenotype of multiminicore disease and congenital muscular dystrophy with spinal rigidity and restrictive respiratory syndrome
  • Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.