DCC Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA550946-Each-of-1 | In Stock | ₹ 46,324.50 |
PA550946 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,324.50
GST (18%): ₹ 8,338.41
Total Price: ₹ 54,662.91
Antigen
DCC
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DCC
Gene Alias
C030036D22Rik; Colorectal cancer suppressor; colorectal tumor suppressor; CRC18; CRCR1; Dcc; DCC netrin 1 receptor; deleted in colorectal cancer protein; deleted in colorectal carcinoma; IGDCC1; Immunoglobulin superfamily DCC subclass member 1; immunoglobulin superfamily, DCC subclass, member 1; MRMV1; Netrin receptor DCC; NTN1R1; putative colorectal tumor suppressor; tumor suppressor protein DCC
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
13176, 1630, 25311
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
ELISA, Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P43146, P70211, Q63155
Gene Symbols
DCC
Immunogen
Synthesized peptide derived from the Internal region of human DCC.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- DCC Polyclonal Antibody detects endogenous levels of DCC protein
- This gene encodes a netrin 1 receptor
- The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand
- The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction
- The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand
- The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma.