PA550956

MRC2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA550956-Each-of-1 In Stock ₹ 46,057.50

PA550956 - Each of 1

₹ 46,057.50

In Stock

Quantity

1

Base Price: ₹ 46,057.50

GST (18%): ₹ 8,290.35

Total Price: ₹ 54,347.85

Antigen

MRC2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MRC2

Gene Alias

CD280; CLEC13E; collagen-binding factor Endo180; C-type lectin domain family 13 member E; C-type mannose receptor 2; Endo180; endocytic receptor (macrophage mannose receptor family); endocytic receptor 180; KIAA0709; Lectin lambda; macrophage mannose receptor 2; mannose receptor C type 2; mannose receptor, C type 2; mKIAA0709; Mrc2; novel lectin; UPARAP; UPAR-associated protein; urokinase-type plasminogen activator receptor-associated protein

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

17534, 498011, 9902

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q4TU93, Q64449, Q9UBG0

Gene Symbols

MRC2

Immunogen

Synthesized peptide derived from the N-terminal region of human Endo180.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • MRC2 Polyclonal Antibody detects endogenous levels of MRC2 protein
  • May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity
  • Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis
  • May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface
  • May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices
  • May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover
  • May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).