PA550967

GCP5 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA550967-Each-of-1 In Stock ₹ 46,502.50

PA550967 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

GCP5

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Tubgcp5

Gene Alias

B130010C12Rik; Gamma-tubulin complex component 5; gamma-tubulin complex component GCP5; GCP5; GCP-5; KIAA1899; mKIAA1899; Tubgcp5; tubulin gamma complex associated protein 5; tubulin, gamma complex associated protein 5

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

114791, 233276, 308663

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ELISA, Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q8BKN5, Q96RT8

Gene Symbols

Tubgcp5

Immunogen

Synthesized peptide derived from the Internal region of human GCP5.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • GCP5 / TUBGCP5 Polyclonal Antibody detects endogenous levels of GCP5 / TUBGCP5 protein
  • The gamma-Tubulin complex is composed of gamma Tubulin and the gamma-Tubulin complex associated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which are essential components of microtubule organizing centers
  • gamma-Tubulin complex components are localized to both the centrosome, where they are involved in microtubule nucleation, and to the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed
  • Although the GCP proteins are related, they have distinct roles which contribute to the proper function of the gamma-Tubulin complex
  • GCP5 ( gamma-Tubulin complex component 5), also known as TUBGCP5, is a 1, 024 amino acid member of the gamma-Tubulin complex and is highly expressed in heart and skeletal muscle
  • Defects in the gene encoding GCP5 are implicated in Prader-Willi syndrome (PWS), a rare genetic disorder associated with obesity, compulsive behavior and lower intellectual ability.