PA551250

eIF3i Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA551250-Each-of-1 In Stock ₹ 46,057.50

PA551250 - Each of 1

₹ 46,057.50

In Stock

Quantity

1

Base Price: ₹ 46,057.50

GST (18%): ₹ 8,290.35

Total Price: ₹ 54,347.85

Antigen

eIF3i

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Eif3i

Gene Alias

36kDa; D4Ertd632e; eIF3 p36; eIF-3-beta; eIF3-beta; Eif3i; eIF3-p36; Eif3s2; Eukaryotic translation initiation factor 3 subunit 2; eukaryotic translation initiation factor 3 subunit I; eukaryotic translation initiation factor 3, subunit 1; eukaryotic translation initiation factor 3, subunit 2 (beta); eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD); eukaryotic translation initiation factor 3, subunit 2 beta, 36kDa; eukaryotic translation initiation factor 3, subunit I; predicted protein of HQ2242; PRO2242; subuni; TGF-beta receptor binding protein; TGF-beta receptor-interacting protein 1; TGFbeta receptor-interacting protein 1; TRIP1; TRIP-1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8668

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q13347

Gene Symbols

Eif3i

Immunogen

Fusion protein of human EIF3I

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total EIF3I protein
  • Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis
  • The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC)
  • The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition
  • The eIF-3 complex is also required for disassembly and recycling of post termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.