PA551313

CCBL1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA551313-Each-of-1 In Stock ₹ 46,502.50

PA551313 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

CCBL1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

KYAT1

Gene Alias

2010009K05Rik; AI182306; beta-lysase, kidney; CCBL1; cysteine conjugate beta lyase 1; cysteine conjugate-beta lyase 1; cysteine conjugate-beta lyase, cytoplasmic; cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase); cysteine-S-conjugate beta-lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase); glutamine transaminase K; glutamine-phenylpyruvate aminotransferase; Glutamine--phenylpyruvate transaminase; Gtk; Kat; KAT1; KATI; KYAT1; kyneurenine aminotransferase; kynurenine aminotransferase 1; Kynurenine aminotransferase I; kynurenine aminotransferase/glutamine transaminase K; kynurenine--oxoglutarate transaminase 1; Kynurenine--oxoglutarate transaminase 1, mitochondrial; kynurenine--oxoglutarate transaminase I

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

311844, 883

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1.2 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q08415, Q16773

Gene Symbols

KYAT1

Immunogen

Full length fusion protein of human CCBL1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total CCBL1 protein
  • Kynurenine aminotransferases KAT I, KAT II, and KAT III belong to the class-I pyridoxal-phosphate-dependent aminotransferase family
  • KAT I is a cytoplasmic protein involved in glutamine catabolism
  • KAT I functions in the catalysis of the transamination of L-kinurenine to form kynurenic acid, a neuroprotective and anticonvulsant metabolite of tryptophan
  • Kynurenic acid is involved in synaptic transmission and has been implicated in a number of neurological disorders including schizophrenia and Huntington's disease
  • KAT I also functions in the metabolism of cysteine conjugates in some halogenated alkenes and alkanes to form reactive metabolites
  • KAT I has three isoforms
  • Isoform 1is the full length protein, isoform 2 lacks amino acids 68-117 and isoform 3 lacks amino acids 251-422
  • Based on sequence similarity, KAT I is thought to function as a homodimer.