PI700226

IRF2 Recombinant Rabbit Monoclonal Antibody (B-80 H53L46), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PI700226-Each-of-1 In Stock ₹ 51,575.50

PI700226 - Each of 1

₹ 51,575.50

In Stock

Quantity

1

Base Price: ₹ 51,575.50

GST (18%): ₹ 9,283.59

Total Price: ₹ 60,859.09

Antigen

IRF2

Classification

Recombinant Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P14316, P23906

Gene Symbols

IRF2

Immunogen

A recombinant protein corresponding to amino acids 121-270.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

ChIP Assay, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

B-80 H53L46

Conjugate

Unconjugated

Gene

IRF2

Gene Alias

9830146E22Rik; AI646973; DKFZp686F0244; Interferon regulatory factor 2; IRF2; Irf-2; OTTHUMP00000218576; OTTHUMP00000218580

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

16363, 290749, 3660

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This antibody is predicted to react with bovine based on sequence homology
  • Intact IgG appears on a non-reducing gel as ∽150 kDa band and upon reduction generating a ∽25 kDa light chain band and a ∽50 kDa heavy chain
  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • IRF2 belongs to the interferon regulatory factor family
  • IRF2 regulates the transcription regulation important to cell proliferation as well as immune responses by binding to the upstream regulatory region of type I IFN and IFNinducible MHC class I genes (the interferon consensus sequence (ICS)) and repression of those genes
  • However, IRF2 also functions as a transcriptional activator of histone H4 by interactions with NF-kappa B.