PI710132

GSK3B Recombinant Polyclonal Antibody (1HCLC), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PI710132-Each-of-1 In Stock ₹ 55,180.00

PI710132 - Each of 1

₹ 55,180.00

In Stock

Quantity

1

Base Price: ₹ 55,180.00

GST (18%): ₹ 9,932.40

Total Price: ₹ 65,112.40

Antigen

GSK3B

Classification

Recombinant Polyclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P49841, Q9WV60

Gene Symbols

GSK3B

Immunogen

Recombinant protein corresponding to amino acids 317–433 of human GSK3 beta

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Western Blot

Clone

1HCLC

Conjugate

Unconjugated

Gene

GSK3B

Gene Alias

7330414F15Rik; 8430431H08Rik; C86142; EC 2.7.11.26; FA; Factor A; fb68h05; fk80d11; glycogen synthase kinase 3; glycogen synthase kinase 3 beta; glycogen synthase kinase 3 beta L homeolog; glycogen synthase kinase 3 beta variant 1; glycogen synthase kinase 3 beta variant 2; glycogen synthase kinase 3 beta variant 3; glycogen synthase kinase 3 beta variant 4; glycogen synthase kinase 3 beta variant 5; glycogen synthase kinase 3 beta, genome duplicate a; glycogen synthase kinase-3 beta; glycogen synthase kinase-3 beta splice variant X1; glycogen synthase kinase-3 beta splice variant X2; glycogen synthase kinase-3 beta splice variant X3; GSK 3 beta; GSK 3B; gsk3; GSK-3; GSK3 beta; GSK-3 beta; GSK-3 beta GSK3B; GSK-3[b]; Gsk3b; GSK-3b; gsk3b.L; gsk3ba; gsk3beta; GSK-3beta; gsk3-beta; GSK3beta isoform; intracellular kinase; pp37; serine/threonine-protein kinase GSK3B; wu:fb68h05; wu:fk80d11; XELAEV_180112401mg; xgsk-3; Xgsk-3 protein

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

2932, 56637

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This antibody is predicted to react with equine, mouse, rabbit and rat based on sequence homology
  • Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific
  • They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody
  • While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains
  • The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production
  • GSK3B is a proline-directed serine/threonine protein kinase involved in energy metabolism, neuronal cell development and body pattern formation
  • It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways
  • GSK3B is a critical component of the Wnt/beta-catenin signaling pathway, and its activity results in the inhibition of Wnt signaling by mediating the degradation of beta-catenin
  • GSK3B is also involved in the Hedgehog, Notch, and insulin signaling pathways.