PI711048

SOX9 Recombinant Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PI711048-Each-of-1 In Stock ₹ 55,536.00

PI711048 - Each of 1

₹ 55,536.00

In Stock

Quantity

1

Base Price: ₹ 55,536.00

GST (18%): ₹ 9,996.48

Total Price: ₹ 65,532.48

Antigen

SOX9

Classification

Recombinant Polyclonal

Conjugate

Unconjugated

Gene

SOX9

Gene Alias

2010306G03Rik; AV220920; CMD1; CMPD1; mKIAA4243; SOX 9; Sox9; SOX-9; Sox9 transcription factor; SRA1; SRXX2; SRXY10; SRY (sex determining region Y)-box 9; SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal); SRY (sex determining region Y)-box9; SRY (sex-determining region Y)-box 9 protein; SRY box 9; SRY-box 9; SRY-Box 9 ; SRY-box containing 9; SRY-box containing gene 9; SRY-box containing protein 9; SRY-box transcription factor 9; SRY-related HMG-box, gene 9; transcription activator Sox9; transcription factor SOX-9

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

6662

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

P48436

Gene Symbols

SOX9

Immunogen

Peptides corresponding to Human SOX9 (aa 4-17, 47-62)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with Monkey, Pig, Mouse Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific
  • They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody
  • While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains
  • The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production
  • SOX9 has a role in sex determination and differentiation of Sertoli cells
  • It is involved in chondrogenesis and regulates the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes
  • Translocation of this gene can cause campomelic dysplasia
  • SOX9 is involved in the formation of testes from the indifferent fetal gonads
  • It is a major molecular component of the neuron-glia switch in developing spinal cord
  • During normal development, SOX9 allows the prostate epithelium to outgrow into the mesenchyme and then provides basal cell support for development and maintenance of the luminal epithelium
  • These functions of SOX9 are subverted in prostate cancer to support tumor growth and invasion
  • SOX9 may direct the formation of neural crest precursors and the development of a range of neural crest derivative
  • It has a transcriptional regulation in melanin production in cells
  • Northern blot analysis shows its expression on adult testis, adult heart, and fetal brain.