CCR2 Recombinant Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PI711255-Each-of-1 | In Stock | ₹ 56,826.50 |
PI711255 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 56,826.50
GST (18%): ₹ 10,228.77
Total Price: ₹ 67,055.27
Antigen
CCR2
Classification
Recombinant Polyclonal
Conjugate
Unconjugated
Gene
Ccr2
Gene Alias
C-C chemokine receptor type 2; C-C CHEMOKINE RECEPTOR TYPE 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (JE/FIC RECEPTOR) (MCP-1 RECEPTOR); C-C CKR-2; C-C motif chemokine receptor 2; Cc-ckr2; CC-CKR-2; Ccr2; CCR-2; Ccr2a; CCR2B; CD192; CD192 antigen; chemoattractant protein-1 receptor; chemokine (C-C motif) receptor 2; chemokine (C-C) receptor 2; chemokine receptor CCR2; Ckr2; Ckr2a; Ckr2b; CMKBR2; hCG_14621; JE/FIC receptor; Mcp1 receptor; MCP-1 receptor; Mcp1r; MCP-1-R; MIP-1 alphaR; mJe-r; Monocyte chemoattractant protein 1 receptor; monocyte chemotactic protein 1 receptor
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
729230
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.
P41597
Gene Symbols
Ccr2
Immunogen
Peptides corresponding to Human CCR2 (aa 6-19, 356-372)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody is predicted to react with Monkey, Sheep, Bovine and Goat
- Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific
- They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody
- While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains
- The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production
- CCR2, a chemokine receptor, is a regulator of monocyte/macrophage traffickings and is upregulated in response to inflammation
- Resistance to HIV-1 infection or delayed progression to AIDS may be linked to CCR2 polymorphisms
- The ligand for CCR2 is monocyte chemoattractant protein (MCP-1), a chemokine produced by endothelial cells, smooth muscle cells, and macrophages
- Activation of monocytes by MCP-1 may mediate the monocytic infiltration of tissues in atherosclerosis and other inflammatory disorders including rheumatoid arthritis, alveolitis, and tumor infiltration
- Two isoforms are produced by alternative splicing
- CCR2 has been reported to be expressed in a wide variety of tissues, including blood, brain, heart, kidney, liver, lung, ovary, pancreas, spinal cord, spleen, thymus, and vessel
- Increased expression of CCR2 has been documented in CD3+ lymphocytes in rheumatoid arthritis
- ESTs have been isolated from liver/spleen and prostate libraries.