PI720264

HTR2C Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PI720264-Each-of-1 In Stock ₹ 51,575.50

PI720264 - Each of 1

₹ 51,575.50

In Stock

Quantity

1

Base Price: ₹ 51,575.50

GST (18%): ₹ 9,283.59

Total Price: ₹ 60,859.09

Antigen

HTR2C

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HTR2C

Gene Alias

5ht1c; 5-HT1C; 5-HT-1C; 5HT-1C; 5-HT1c receptor; 5-HT2C; 5-HT-2C; 5HT2C Receptor; 5-HT2C receptor; 5-HT2cR; 5HTR2C; 5-HTR2C; 5-hydroxytryptamine (serotonin) receptor 2C; 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled; 5-hydroxytryptamine receptor 1C; 5-hydroxytryptamine receptor 2C; HGNC:5295; HTR1C; Htr2c; RP11-810O3.1; RP23-15B7.1; serotonin 1c receptor; serotonin 5-HT-1C receptor; serotonin 5-HT-2C receptor; serotonin receptor 2C; SR1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

15560, 3358

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.

P28335, P34968

Gene Symbols

HTR2C

Immunogen

Protein corresponding to Human HTR2C (aa 236-311)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides
  • The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide
  • The purified antibody is tested for its functionality in various relevant research applications
  • The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature
  • This antibody is predicted to react with Monkey, Horse, Pig, Goat, Cat and Rabbit Serotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways
  • This gene encodes the 2C subtype of serotonin receptor and its mRNA is subject to multiple RNA editing events, where genomically encoded adenosine residues are converted to inosines
  • RNA editing is predicted to alter amino acids within the second intracellular loop of the 5-HT2C receptor and generate receptor isoforms that differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, thus modulating serotonergic neurotransmission in the central nervous system
  • Studies in humans have reported abnormalities in patterns of 5-HT2C editing in depressed suicide victims.