PI720270
E2F5 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PI720270-Each-of-1 | In Stock | ₹ 50,596.50 |
PI720270 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,596.50
GST (18%): ₹ 9,107.37
Total Price: ₹ 59,703.87
Antigen
E2F5
Classification
Polyclonal
Conjugate
Unconjugated
Gene
E2F5
Gene Alias
AU024671; E2F transcription factor 5; E2F transcription factor 5, p130-binding; E2f5; E2F-5; Transcription factor E2F5
Host Species
Rabbit
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
1875
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.
Q15329
Gene Symbols
E2F5
Immunogen
Protein corresponding to human E2F5 (aa200-346)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody is predicted to react with Monkey, Pig, Mouse E2F5 is a member of the E2F family of transcription factors
- The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses
- The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family
- These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain
- This protein is differentially phosphorylated and is expressed in a wide variety of human tissues
- It has higher identity to E2F4 than to other family members
- Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB
- Alternative splicing results in multiple variants encoding different isoforms.