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PIMA1014

SOX2 Monoclonal Antibody (20G5), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA1014-Each-of-1 In Stock ₹ 43,120.50

PIMA1014 - Each of 1

₹ 43,120.50

In Stock

Quantity

1

Base Price: ₹ 43,120.50

GST (18%): ₹ 7,761.69

Total Price: ₹ 50,882.19

Antigen

SOX2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide

Gene Accession No.

P48431, P48432

Gene Symbols

SOX2

Immunogen

Full-length human recombinant protein expressed in bacteria

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Canine, Fish, Human, Mouse

Product Type

Antibody

Isotype

IgG1 κ

Applications

ChIP Assay, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

20G5

Conjugate

Unconjugated

Gene

SOX2

Gene Alias

ANOP3; cb236; Delta EF2a; lcc; MCOPS3; MCOPS3 (Microphthalmia Syndromic type 3); RGD1565646; sex determining region Y-box 2; SOX 2; SOX2; Sox-2; soxp; SRY (sex determining region Y) box 2; SRY (sex determining region Y)-box 2; SRY box 2; SRY related HMG box 2; SRY-box 2; SRY-box 2; SOX2; SRY-box containing gene 2; SRY-box transcription factor 2; SRY-related HMG-box gene 2; transcription factor SOX2; transcription factor SOX-2; wu:fb83g04; wu:fc14d07; ysb; zgc:65860; zgc:77389

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

20674, 488092, 6657

Content And Storage

-20°C

Form

Liquid

Description

  • Western blot analysis of MA1-014 specifically detects SOX2 protein at ∽36 kDa in the nucleus of human and mouse embryonal carcinoma and iPS cells
  • SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate
  • The product of the SOX2 gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach
  • The SOX2 gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT)
  • Further, SOX2 protein may act as a transcriptional activator after forming a protein complex with other proteins
  • Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation, optic nerve hypoplasia and syndromic microphthalmia.